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Catalyst

berberineFinding

Berberine decreases triglycerides

lowersModerate evidenceFindingreplicated ×3

01 · The sentence it was drawn from

“The comprehensive analysis revealed that berberine exhibited potential in reducing TG levels in NAFLD patients (SMD = − 0.59, 95% CI [− 0.86, − 0.31], P < 0.0001, I2 = 73%; Fig. 6).”
Quoted verbatim from The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review.
This finding among the 108 findings on its endpoint

berberine

Triglycerides

lowers

Effect as reported

−0.59standardised mean difference

CI −0.86 to −0.31

Who
Adults with NAFLD in pooled RCTs; berberine added to metformin in both-arm-metformin trials (patients with comorbid diabetes) or compared with lifestyle intervention or placebo
Dose studied
berberine 0.6 g to 2 g daily in 9 RCTs, 6.35 g daily in one; 7 to 24 weeks

Moderate evidencePMID 38429794 · 2024

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Journal of translational medicine
What else it reported5 findings · 1 compound · 5 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZAE7XF5H84M46DP1YSW2N2