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Catalyst

coenzyme Q10Finding

Coenzyme Q10 decreases HOMA-IR

lowersModerate evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“A meta‐analysis of 11 trial arms (324 participants in the CoQ10 groups and 325 in the control groups) showed that CoQ10 supplementation significantly reduced HOMA‐IR (WMD = −0.82; 95% CI: −1.36, −0.28; I 2 = 90.0 %; p < 0.001).”
Quoted verbatim from Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
This finding among the 63 findings on its endpoint

coenzyme Q10

HOMA-IR

lowers

Effect as reported

−0.82mean difference

CI −1.36 to −0.28

Who
Adults with disorders of lipid and/or glucose metabolism, pooled randomized trials of CoQ10 alone or with co-interventions, against placebo, no treatment or the same co-intervention without CoQ10
Dose studied
60 to 600 mg/day, pooled

Moderate evidencePMID 42192187 · 2026

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Journal of diabetes research
What else it reported11 findings · 1 compound · 11 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5K6P54SAHT6S9W99R0TKR