Coenzyme Q10 decreases interleukin‑6 concentration

lowersModerate evidenceFindingreplicated ×2

01 · The sentence it was drawn from

“The pooled analysis indicated that CoQ10 supplementation significantly reduced IL‐6 levels (SMD = −0.42; 95% CI: −0.79, −0.05; I 2 = 74.0 %; p < 0.001).”

Quoted verbatim from Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.

This finding among the 81 findings on its endpoint

coenzyme Q10

Interleukin-6 concentration

lowers

Effect as reported

−0.42standardised mean difference

CI −0.79 to −0.05

Who: Adults with disorders of lipid and/or glucose metabolism; ten randomised trials pooled, CoQ10 alone or with co-interventions against a control receiving the same co-intervention
Dose studied: CoQ10 60 to 600 mg/day, pooled; 4 to 24 weeks

Moderate evidencePMID 42192187 · 2026

02 · The study

Study: meta-analysis
Duration: not reported

Evidence, by strength

strong
moderatethis finding
limited
very limited
insufficient

03 · The paper

Journal of diabetes research

Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.

2026PMID 42192187doi 10.1155/jdr/5587445

What else it reported11 findings · 1 compound · 11 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y3PW9BWMKHWRPF8Q5G8QHS