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Catalyst

coenzyme Q10Finding

Source withdrawn and superseded by an update. Do not rely on it.

Coenzyme Q10 has no detected effect on withdrawal due to adverse events

no difference foundVery limited evidenceFinding

01 · The sentence it was drawn from

“In safety outcomes, only the risk ratios (RR) of pharyngitis (RR 1.04, 95% CI 0.18 to 5.89) and diarrhea (RR 1.39, 95% CI 0.62 to 3.16) are mild elevated between coenzyme Q10 therapy and placebo and there were no differences in the number of withdrawals due to adverse effects (RR 0.61, 95% CI 0.23 to 1.62).”
Quoted verbatim from Coenzyme Q10 for Parkinson's disease.
This finding among the 12 findings on its endpoint

coenzyme Q10

Withdrawal due to adverse events

no difference found

Effect as reported

0.61risk ratio

CI 0.23 to 1.62

Who
patients with early and midstage Parkinson's disease; Cochrane meta-analysis of 4 RCTs, 452 patients, coenzyme Q10 versus placebo
Dose studied
1200 mg/d for 16 months

Very limited evidencePMID 22161420 · 2011

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

The Cochrane database of systematic reviews

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M38RFSM3H9K69VMW49MXCEXY