yellow nail syndrome
MONDO:0007921Mondo
Findings
No curated finding names yellow nail syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A very rare syndromic disorder characterized by the variable triad of characteristic yellow nails, chronic respiratory manifestations, and primary lymphedema.
Definition from the Mondo Disease Ontology (MONDO:0007921), read 2026-09-29. CC BY 4.0.
Features
24 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal fingernail morphologyHPOHP:0001231
- Very frequent (80% to 99% of cases)
- Abnormal toenail morphologyHPOHP:0008388
- Very frequent (80% to 99% of cases)
- BronchiectasisHPOHP:0002110
- Very frequent (80% to 99% of cases)
- Fingernail dysplasiaHPOHP:0100798
- Very frequent (80% to 99% of cases)
- Hypoplasia of lymphatic vesselsHPOHP:0003759
- Very frequent (80% to 99% of cases)
- LymphedemaHPOHP:0001004
- Very frequent (80% to 99% of cases)
- Toenail dysplasiaHPOHP:0100797
- Very frequent (80% to 99% of cases)
- Yellow nailsHPOHP:0011367
- Very frequent (80% to 99% of cases)
- CoughHPOHP:0012735
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- PleuritisHPOHP:0002102
- Frequent (30% to 79% of cases)
- Recurrent respiratory infectionsHPOHP:0002205
- Frequent (30% to 79% of cases)
Show the remaining 12
- RhinitisHPOHP:0012384
- Frequent (30% to 79% of cases)
- SinusitisHPOHP:0000246
- Frequent (30% to 79% of cases)
- Biliary tract neoplasmHPOHP:0100574
- Occasional (5% to 29% of cases)
- Generalized abnormality of skinHPOHP:0011354
- Occasional (5% to 29% of cases)
- ImmunodeficiencyHPOHP:0002721
- Occasional (5% to 29% of cases)
- NeoplasmHPOHP:0002664
- Occasional (5% to 29% of cases)
Where it sits
Other names
2 names
Resolves to: yellow nail syndrome
- Also called
- lymphedema with yellow nailsYNS