univentricular heart
Findings
No curated finding names univentricular heart yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Univentricular heart (UVH) is a severe congenital cardiac malformation characterized by both atria related entirely or almost entirely to one functionally single ventricular chamber. The clinical manifestations include congestive heart failure, failure to thrive, cyanosis, hypoxemia and neurodevelopmental disabilities.
Definition from the Mondo Disease Ontology (MONDO:0015451), read 2026-09-29. CC BY 4.0.
Features
14 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Pulmonary venous hypertensionHPOHP:0030950
- Very frequent (80% to 99% of cases)
- Valvular pulmonary stenosisHPOHP:0034350
- Very frequent (80% to 99% of cases)
- Congestive heart failureHPOHP:0001635
- Frequent (30% to 79% of cases)
- Failure to thriveHPOHP:0001508
- Frequent (30% to 79% of cases)
- Heart murmurHPOHP:0030148
- Frequent (30% to 79% of cases)
- Hypoplastic left ventricleHPOHP:0004383
- Frequent (30% to 79% of cases)
- Respiratory distressHPOHP:0002098
- Frequent (30% to 79% of cases)
- TachypneaHPOHP:0002789
- Frequent (30% to 79% of cases)
- ArrhythmiaHPOHP:0011675
- Occasional (5% to 29% of cases)
- CardiomegalyHPOHP:0001640
- Occasional (5% to 29% of cases)
- CyanosisHPOHP:0000961
- Occasional (5% to 29% of cases)
- Esophageal varixHPOHP:0002040
- Occasional (5% to 29% of cases)
Show the remaining 2
- HepatomegalyHPOHP:0002240
- Occasional (5% to 29% of cases)
- HypoxemiaHPOHP:0012418
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
- Narrower terms (1)
Other names
1 name
Resolves to: univentricular heart
- Also called
- Double inlet left ventricle