unilateral focal polymicrogyria
MONDO:0017093Mondo
Findings
No curated finding names unilateral focal polymicrogyria yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Unilateral focal polymicrogyria (BFPP) is the mildest sub-type of polymicrogyria (PMG), a cerebral cortical malformation characterized by excessive cortical folding and abnormal cortical layering, that affects only one small region of the brain and that may show no neurologic involvement.
Definition from the Mondo Disease Ontology (MONDO:0017093), read 2026-09-29. CC BY 4.0.
Features
29 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Cerebral cortical hemiatrophyHPOHP:0100308
- Very frequent (80% to 99% of cases)
- Cortical dysplasiaHPOHP:0002539
- Very frequent (80% to 99% of cases)
- Focal motor seizureHPOHP:0011153
- Very frequent (80% to 99% of cases)
- Global developmental delayHPOHP:0001263
- Very frequent (80% to 99% of cases)
- HemiparesisHPOHP:0001269
- Very frequent (80% to 99% of cases)
- Intellectual disabilityHPOHP:0001249
- Very frequent (80% to 99% of cases)
- SeizureHPOHP:0001250
- Very frequent (80% to 99% of cases)
- Spastic hemiparesisHPOHP:0011099
- Very frequent (80% to 99% of cases)
- Abnormality of somatosensory evoked potentialsHPOHP:0007377
- Frequent (30% to 79% of cases)
- Attention deficit hyperactivity disorderHPOHP:0007018
- Frequent (30% to 79% of cases)
- Bilateral tonic-clonic seizure with focal onsetHPOHP:0007334
- Frequent (30% to 79% of cases)
- EEG with frontal focal spikesHPOHP:0012015
- Frequent (30% to 79% of cases)
Show the remaining 17
- EEG with temporal focal spikesHPOHP:0012018
- Frequent (30% to 79% of cases)
- Mental deteriorationHPOHP:0001268
- Frequent (30% to 79% of cases)
- Mild intellectual disabilityHPOHP:0001256
- Frequent (30% to 79% of cases)
- Moderate intellectual disabilityHPOHP:0002342
- Frequent (30% to 79% of cases)
- Abnormal nonverbal communicative behaviorHPOHP:0000758
- Occasional (5% to 29% of cases)
- Aggressive behaviorHPOHP:0000718
- Occasional (5% to 29% of cases)
Where it sits
- A kind of