undifferentiated pleomorphic sarcoma
MONDO:0002142Mondo
Findings
No curated finding names undifferentiated pleomorphic sarcoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An undifferentiated soft tissue sarcoma characterized by the presence of a pleomorphic malignant cellular infiltrate. It is also known as malignant fibrous histiocytoma.
Definition from the Mondo Disease Ontology (MONDO:0002142), read 2026-09-29. CC BY 4.0.
Features
9 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal peritoneum morphologyHPOHP:0002585
- Very frequent (80% to 99% of cases)
- Abnormality of the lower limbHPOHP:0002814
- Very frequent (80% to 99% of cases)
- Soft tissue sarcomaHPOHP:0030448
- Very frequent (80% to 99% of cases)
- Abnormality of the musculatureHPOHP:0003011
- Frequent (30% to 79% of cases)
- FeverHPOHP:0001945
- Frequent (30% to 79% of cases)
- Abnormality of the upper limbHPOHP:0002817
- Occasional (5% to 29% of cases)
- AnorexiaHPOHP:0002039
- Occasional (5% to 29% of cases)
- FatigueHPOHP:0012378
- Occasional (5% to 29% of cases)
- Weight lossHPOHP:0001824
- Occasional (5% to 29% of cases)
Where it sits
Other names
22 names
Resolves to: undifferentiated pleomorphic sarcoma
- Also called
- adult malignant fibrous histiocytomaadult unclassified pleomorphic sarcomaadult undifferentiated pleomorphic sarcomafibrous histiocytoma, malignantfibrous histiocytoma, malignant (morphologic abnormality)fibroxanthosarcomafibroxanthosarcoma (morphologic abnormality)histiocytoma, fibrous, malignantmalignant fibrous cytomamalignant fibrous histiocytomamalignant fibrous histiocytoma of soft tissue and bonemalignant fibrous histiocytoma of the soft tissue and bonemalignant fibroxanthomaMFHStoriform-pleomorphic fibrous histiocytoma