undifferentiated high grade pleomorphic sarcoma of bone
Findings
No curated finding names undifferentiated high grade pleomorphic sarcoma of bone yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare, high-grade pleomorphic malignant neoplasm arising from the bone. It usually presents with pain which may or may not be associated with swelling in the affected area. It is characterized by the presence of spindle-shaped cells, polygonal or epithelioid cells, multinucleated giant cells, and inflammatory cells. The neoplastic cells exhibit nuclear pleomorphism and high mitotic activity. It metastasizes frequently, most often in the lungs.
Definition from the Mondo Disease Ontology (MONDO:0002618), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
5 names
Resolves to: undifferentiated high grade pleomorphic sarcoma of bone
- Also called
- malignant bone fibrous histiocytomamalignant fibrous histiocytoma of bonemalignant fibrous histiocytoma of the boneundifferentiated high grade pleomorphic sarcomaundifferentiated high-grade pleomorphic sarcoma