trigeminal neuralgia
Findings
No curated finding names trigeminal neuralgia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain lasts a few seconds to a few minutes, and usually on only one side of the face. It can also cause muscle spasms in the face the same time as the pain. The pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of theface), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor or cyst. In some cases, the cause is unknown. Treatment options include medicines, surgery, and complementary approaches.
Definition from the Mondo Disease Ontology (MONDO:0008599), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Trigeminal neuralgiaHPOHP:0100661
- Obligate (100% of cases)
- AllodyniaHPOHP:0012533
- Very frequent (80% to 99% of cases)
- Cluster headacheHPOHP:0012199
- Very frequent (80% to 99% of cases)
- DepressionHPOHP:0000716
- Very frequent (80% to 99% of cases)
- Episodic paroxysmal anxietyHPOHP:0000740
- Frequent (30% to 79% of cases)
- Feeding difficultiesHPOHP:0011968
- Frequent (30% to 79% of cases)
- Mandibular pain
Show the remaining 5
- CNS demyelinationHPOHP:0007305
- Occasional (5% to 29% of cases)
- Cranial nerve compressionHPOHP:0001293
- Occasional (5% to 29% of cases)
- NeoplasmHPOHP:0002664
- Occasional (5% to 29% of cases)
- Ocular painHPOHP:0200026
- Occasional (5% to 29% of cases)
- Peripheral demyelinationHPOHP:0011096
- Occasional (5% to 29% of cases)
Where it sits
Other names
2 names
Resolves to: trigeminal neuralgia
- Also called
- neuralgia of trigeminal nervetrigeminal nerve neuralgia