transient myeloproliferative syndrome
MONDO:0008040Mondo
Findings
No curated finding names transient myeloproliferative syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission.
Definition from the Mondo Disease Ontology (MONDO:0008040), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
11 names
Resolves to: transient myeloproliferative syndrome
- Also called
- leukemia, transient, of Down syndromeMSTTAMTMDtransient abnormal myelopoiesisTransient abnormal myelopoiesis associated with Down syndrometransient leukaemiatransient leurkemia of Down syndrometransient myeloproliferative diseasetransient myeloproliferative disordertransient myeloproliferative syndrome (disease)