thymic neuroendocrine tumor
Findings
No curated finding names thymic neuroendocrine tumor yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Thymic endocrine tumor is a rare, malignant, primary thymic neoplasm originating from neuroendocrine cells, presenting as a mass within the anterior mediastinum. Patients typically present with nonspecific symptoms, such as chest pain, cough, shortness of breath, or in some cases, superior vena cava syndrome, although patients could be asymptomatic during the early stages or present with multiple endocrine neoplasia type I. Ectopic production of ACTH and serotonin can lead to Cushing syndrome and carcinoid sydrome, respectively.
Definition from the Mondo Disease Ontology (MONDO:0019964), read 2026-09-29. CC BY 4.0.
Features
24 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Neoplasm of the thymusHPOHP:0100521
- Obligate (100% of cases)
- Neuroendocrine neoplasmHPOHP:0100634
- Obligate (100% of cases)
- Abnormal mediastinum morphologyHPOHP:0045026
- Very frequent (80% to 99% of cases)
- Mediastinal lymphadenopathyHPOHP:0100721
- Very frequent (80% to 99% of cases)
- Abnormal breath soundHPOHP:0030829
- Frequent (30% to 79% of cases)
- Abnormal vena cava morphologyHPOHP:0005345
- Frequent (30% to 79% of cases)
- Carcinoid tumor
Show the remaining 12
- Neoplasm of the endocrine systemHPOHP:0100568
- Frequent (30% to 79% of cases)
- Prominent veins on trunkHPOHP:0007457
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- Calcium nephrolithiasisHPOHP:0004724
- Occasional (5% to 29% of cases)
- HypercalcemiaHPOHP:0003072
- Occasional (5% to 29% of cases)
- Increased circulating prolactin concentrationHPOHP:0000870
- Occasional (5% to 29% of cases)
Where it sits
- Narrower terms (1)
Other names
6 names
Resolves to: thymic neuroendocrine tumor
- Also called
- neuroendocrine neoplasm of thymusthymus NETthymus neuroendocrine neoplasmthymus neuroendocrine tumorthymus neuroendocrine tumor, well differentiated, low or intermediate gradethymus neuroendocrine tumour