thromboangiitis obliterans
Findings
No curated finding names thromboangiitis obliterans yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.
Definition from the Mondo Disease Ontology (MONDO:0008889), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Arterial thrombosisHPOHP:0004420
- Very frequent (80% to 99% of cases)
- GangreneHPOHP:0100758
- Very frequent (80% to 99% of cases)
- Sensory neuropathyHPOHP:0000763
- Very frequent (80% to 99% of cases)
- Skin ulcerHPOHP:0200042
- Very frequent (80% to 99% of cases)
- VasculitisHPOHP:0002633
- Very frequent (80% to 99% of cases)
- AcrocyanosisHPOHP:0001063
- Frequent (30% to 79% of cases)
- ArthralgiaHPOHP:0002829
- Frequent (30% to 79% of cases)
- Digital ischemiaHPOHP:0033402
- Frequent (30% to 79% of cases)
- Intermittent claudicationHPOHP:0004417
- Frequent (30% to 79% of cases)
- Livedo reticularisHPOHP:0033505
- Frequent (30% to 79% of cases)
- ParesthesiaHPOHP:0003401
- Frequent (30% to 79% of cases)
- Raynaud phenomenonHPOHP:0030880
- Frequent (30% to 79% of cases)
Show the remaining 5
- AcroparesthesiaHPOHP:0031006
- Occasional (5% to 29% of cases)
- HyperhidrosisHPOHP:0000975
- Occasional (5% to 29% of cases)
- InsomniaHPOHP:0100785
- Occasional (5% to 29% of cases)
- Superficial thrombophlebitisHPOHP:0002638
- Occasional (5% to 29% of cases)
- Arterial occlusionHPOHP:0025324
- Very rare (1% to 4% of cases)
Where it sits
Other names
2 names
Resolves to: thromboangiitis obliterans
- Also called
- Buerger's Diseasethromboangiitis obliterans [Buerger's disease]