Tako-tsubo cardiomyopathy
MONDO:0019018Mondo
Findings
No curated finding names Tako-tsubo cardiomyopathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Takotsubo cardiomyopathy (TC) is a recently described acute cardiac syndrome that mimics acute myocardial infarction and is characterized by ischemic chest symptoms, an elevated ST segment on electrocardiogram, and elevated levels of cardiac disease markers.
Definition from the Mondo Disease Ontology (MONDO:0019018), read 2026-09-29. CC BY 4.0.
Features
33 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Mildly reduced left ventricular ejection fractionHPOHP:0012663
- Very frequent (80% to 99% of cases)
- Chest painHPOHP:0100749
- Frequent (30% to 79% of cases)
- Increased circulating troponin T concentrationHPOHP:0410174
- Frequent (30% to 79% of cases)
- Reduced contraction of the left ventricular apexHPOHP:0031483
- Frequent (30% to 79% of cases)
- ST segment elevationHPOHP:0012251
- Frequent (30% to 79% of cases)
- T-wave inversionHPOHP:0010872
- Frequent (30% to 79% of cases)
- Abnormal circulating B-type natriuretic peptide concentrationHPOHP:0031138
- Occasional (5% to 29% of cases)
- Angina pectorisHPOHP:0001681
- Occasional (5% to 29% of cases)
- Decreased QRS voltageHPOHP:0025077
- Occasional (5% to 29% of cases)
- Dilatation of the ventricular cavityHPOHP:0006698
- Occasional (5% to 29% of cases)
- DyspneaHPOHP:0002094
- Occasional (5% to 29% of cases)
- HypertensionHPOHP:0000822
- Occasional (5% to 29% of cases)
Reported absent (4)
- Abnormal coronary artery morphologyHPOHP:0006704
- Coronary artery atherosclerosisHPOHP:0001677
- Coronary artery stenosisHPOHP:0005145
- MyocarditisHPOHP:0012819
Show the remaining 21
- HypotensionHPOHP:0002615
- Occasional (5% to 29% of cases)
- Left ventricular apical dyskinesisHPOHP:6001073
- Occasional (5% to 29% of cases)
- Low-output congestive heart failureHPOHP:0009805
- Occasional (5% to 29% of cases)
- Mildly elevated creatine kinaseHPOHP:0008180
- Occasional (5% to 29% of cases)
- ObesityHPOHP:0001513
- Occasional (5% to 29% of cases)
- PalpitationsHPOHP:0001962
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
9 names
Resolves to: Tako-tsubo cardiomyopathy
- Also called
- ampulla cardiomyopathyapical ballooning syndromeballooning cardiomyopathybroken heart syndromestress cardiomyopathyTako-Tsubo syndromeTakotsubo CardiomyopathyTakotsubo syndrometransient left ventricular apical ballooning syndrome