T-B+ severe combined immunodeficiency
MONDO:0044200Mondo
Findings
No curated finding names T-B+ severe combined immunodeficiency yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
T-B+ severe combined immunodeficiency (SCID) is a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes with presence of B lymphocytes, resulting in early-onset severe respiratory viral, bacterial or fungal infections, diarrhea and failure to thrive.
Definition from the Mondo Disease Ontology (MONDO:0044200), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
- Narrower terms (10)
- combined immunodeficiency, X-linked
- immunodeficiency 104
- lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome
- severe combined immunodeficiency due to CORO1A deficiency
- severe combined immunodeficiency due to LAT deficiency
- T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta
- T-B+ severe combined immunodeficiency due to CD45 deficiency
- T-B+ severe combined immunodeficiency due to gamma chain deficiency
- T-B+ severe combined immunodeficiency due to IL-7Ralpha deficiency
- T-B+ severe combined immunodeficiency due to JAK3 deficiency
Other names
2 names
Resolves to: T-B+ severe combined immunodeficiency
- Also called
- T-B+ SCIDT-cell negative B-cell positive SCID