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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

Disease

systemic monochloroacetate poisoning

MONDO:0019545Mondo

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Findings

No curated finding names systemic monochloroacetate poisoning yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

Systemic monochloroacetate poisoning is a rare, life-threatening intoxication with monochloroacetic acid (mainly through the skin, but also by inhalation or ingestion). It is characterized by vomiting, diarrhea and central nervous system (CNS)-excitability (disorientation, delirium, convulsions) as early signs of systemic poisoning, followed by CNS-depression, coma and cerebral edema. Additional signs include heart involvement (severe myocardial depression, shock, arrhythmias, nonspecific myocardial damage), severe metabolic acidosis, hypokalemia, hypocalcemia and progressive renal failure leading to anuria. Myoglobinemia and leukocytosis may occur. Manifestations may be delayed for 1-4 hours.

Definition from the Mondo Disease Ontology (MONDO:0019545), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: poisoning