systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease
Findings
No curated finding names systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Systemic mastocytosis with an associated clonal hematological non-mast cell lineage disease is a form of systemic mastocytosis (SM) associated with malignancy (other than mast cell leukemia).
Definition from the Mondo Disease Ontology (MONDO:0020332), read 2026-09-29. CC BY 4.0.
Features
45 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal mast cell morphologyHPOHP:0100494
- Very frequent (80% to 99% of cases)
- Elevated total serum tryptaseHPOHP:0031901
- Very frequent (80% to 99% of cases)
- Hematological neoplasmHPOHP:0004377
- Very frequent (80% to 99% of cases)
- Myeloid leukemiaHPOHP:0012324
- Very frequent (80% to 99% of cases)
- Bone marrow hypercellularityHPOHP:0031020
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
Show the remaining 33
- Normocytic anemiaHPOHP:0001897
- Frequent (30% to 79% of cases)
- PallorHPOHP:0000980
- Frequent (30% to 79% of cases)
- PruritusHPOHP:0000989
- Frequent (30% to 79% of cases)
- ThrombocytopeniaHPOHP:0001873
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- Abdominal painHPOHP:0002027
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
12 names
Resolves to: systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease
- Also called
- SM-AHNSM-AHNMDSMAHNsystemic mastocytosis with an associated haematological neoplasmsystemic mastocytosis with an associated haematological neoplasm (SM-AHN)systemic mastocytosis with an associated hematological neoplasmsystemic mastocytosis with an associated hematological neoplasm (SM-AHN)systemic mastocytosis with associated clonal haematological non-mast-cell lineage diseasesystemic mastocytosis with associated clonal hematological non-mast cell lineage diseasesystemic mastocytosis with associated clonal hematological non-mast-cell lineage diseasesystemic mastocytosis with associated clonal, hematologic non-mast-cell lineage disease (morphologic abnormality)systemic mastocytosis with associated hematologic neoplasm