systemic lupus erythematosus 17
MONDO:0859083Mondo
Findings
No curated finding names systemic lupus erythematosus 17 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- X-linked dominant inheritance
- Onset and course
- Juvenile onset · Early young adult onset
HPO, annotations 2026-09-02
Features
23 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Antinuclear antibody positivityHPOHP:0003493
- 3 of 3 reported patients
- ArthralgiaHPOHP:0002829
- 2 of 3 reported patients
- Decreased circulating complement C3 concentrationHPOHP:0005421
- 2 of 3 reported patients
- Systemic lupus erythematosusHPOHP:0002725
- 2 of 3 reported patients
- AlopeciaHPOHP:0001596
- 1 of 3 reported patients
- Anti-aquaporin 4 antibody positivityHPOHP:0033342
- 1 of 3 reported patients
- AnxietyHPOHP:0000739
- 1 of 3 reported patients
- Autoimmune thrombocytopeniaHPOHP:0001973
- 1 of 3 reported patients
- ChoreaHPOHP:0002072
- 1 of 3 reported patients
- Decreased circulating complement C4 concentrationHPOHP:0045042
- 1 of 3 reported patients
- Decreased total leukocyte countHPOHP:0001882
- 1 of 3 reported patients
- Decreased total lymphocyte countHPOHP:0001888
- 1 of 3 reported patients
Show the remaining 11
- FeverHPOHP:0001945
- 1 of 3 reported patients
- HeadacheHPOHP:0002315
- 1 of 3 reported patients
- Hypertensive crisisHPOHP:0100735
- 1 of 3 reported patients
- Malar rashHPOHP:0025300
- 1 of 3 reported patients
- Mitral regurgitationHPOHP:0001653
- 1 of 3 reported patients
- MyelitisHPOHP:0012486
- 1 of 3 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TLR7HGNC:15631
- Moderate · ClinGen · X-linked · 2024
- Moderate · PanelApp Australia · X-linked · 2025
- Moderate · Baylor College of Medicine Research Center · X-linked · 2025
Where it sits
- A kind of