syndactyly type 4
Findings
No curated finding names syndactyly type 4 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A very rare congenital distal limb malformation characterized by complete bilateral syndactyly (involving all digits 1 to 5).
Definition from the Mondo Disease Ontology (MONDO:0008515), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
10 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- 1-5 finger cutaneous syndactylyHPOHP:0010708
- Very frequent (80% to 99% of cases)
- Camptodactyly of fingerHPOHP:0100490
- Very frequent (80% to 99% of cases)
- Hand polydactylyHPOHP:0001161
- Very frequent (80% to 99% of cases)
- 6 metacarpalsHPOHP:0001501
- Frequent (30% to 79% of cases)
- Foot polydactylyHPOHP:0001829
- Frequent (30% to 79% of cases)
- Short tibiaHPOHP:0005736
- Frequent (30% to 79% of cases)
- Toe syndactyly
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
Other names
3 names
Resolves to: syndactyly type 4
- Also called
- LMBR1 non-syndromic syndactylynon-syndromic syndactyly caused by mutation in LMBR1polysyndactyly, Haas type