symphalangism with multiple anomalies of hands and feet
Findings
No curated finding names symphalangism with multiple anomalies of hands and feet yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Symphalangism with multiple anomalies of hands and feet is an exceedingly rare syndrome described in one family and characterized by proximal symphalangism and multiple hand and feet disorders (syndactyly, clinodactyly, hypoplasia of the thenar and hypothenar eminences, and a distinctive dermatoglyphic pattern). There have been no further descriptions in the literature since 1981.
Definition from the Mondo Disease Ontology (MONDO:0008510), read 2026-09-29. CC BY 4.0.
Features
22 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Fifth finger symphalangismHPOHP:0004218
- Very frequent (80% to 99% of cases)
- Fourth finger symphalangismHPOHP:0004197
- Very frequent (80% to 99% of cases)
- Reduced proximal interphalangeal joint spaceHPOHP:0006019
- Very frequent (80% to 99% of cases)
- Abnormal dermatoglyphicsHPOHP:0007477
- Frequent (30% to 79% of cases)
- Abnormal distal toe phalanx morphologyHPOHP:0010182
- Frequent (30% to 79% of cases)
- Absent distal interphalangeal creasesHPOHP:0001032
- Frequent (30% to 79% of cases)
Show the remaining 10
- Small hypothenar eminenceHPOHP:0010487
- Frequent (30% to 79% of cases)
- Small thenar eminenceHPOHP:0001245
- Frequent (30% to 79% of cases)
- Toe symphalangismHPOHP:0010179
- Frequent (30% to 79% of cases)
- Toe syndactylyHPOHP:0001770
- Frequent (30% to 79% of cases)
- 2-5 finger cutaneous syndactylyHPOHP:0005650
- Occasional (5% to 29% of cases)
- Abnormal finger flexion creaseHPOHP:0006143
- Occasional (5% to 29% of cases)
Where it sits
Other names
1 name
Resolves to: symphalangism with multiple anomalies of hands and feet
- Also called
- Learman syndrome