subacute sclerosing panencephalitis
MONDO:0009835Mondo
Findings
No curated finding names subacute sclerosing panencephalitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A chronic progressive encephalitis that develops a few years after measles infection and presents with a demyelination of the cerebral cortex.
Definition from the Mondo Disease Ontology (MONDO:0009835), read 2026-09-29. CC BY 4.0.
Features
35 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Atypical behaviorHPOHP:0000708
- Very frequent (80% to 99% of cases)
- Mental deteriorationHPOHP:0001268
- Very frequent (80% to 99% of cases)
- MyoclonusHPOHP:0001336
- Very frequent (80% to 99% of cases)
- Abnormal autonomic nervous system physiologyHPOHP:0012332
- Frequent (30% to 79% of cases)
- Akinetic mutismHPOHP:0012672
- Frequent (30% to 79% of cases)
- Anti-measles antibody positivityHPOHP:0430088
- Frequent (30% to 79% of cases)
- Brain atrophyHPOHP:0012444
- Frequent (30% to 79% of cases)
- ChorioretinitisHPOHP:0012424
- Frequent (30% to 79% of cases)
- DelusionHPOHP:0000746
- Frequent (30% to 79% of cases)
- DementiaHPOHP:0000726
- Frequent (30% to 79% of cases)
- DepressionHPOHP:0000716
- Frequent (30% to 79% of cases)
- DystoniaHPOHP:0001332
- Frequent (30% to 79% of cases)
Show the remaining 23
- EEG with periodic complexesHPOHP:0010856
- Frequent (30% to 79% of cases)
- Gait disturbanceHPOHP:0001288
- Frequent (30% to 79% of cases)
- HallucinationsHPOHP:0000738
- Frequent (30% to 79% of cases)
- IrritabilityHPOHP:0000737
- Frequent (30% to 79% of cases)
- LethargyHPOHP:0001254
- Frequent (30% to 79% of cases)
- Loss of speechHPOHP:0002371
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
6 names
Resolves to: subacute sclerosing panencephalitis
- Also called
- Immunosuppressive measles encephalitisSSPESubacute inclusion body encephalitisSubacute sclerosing panencephalitis (disorder) [ambiguous]Van Bogaert diseaseVan Bogaert encephalitis