stromal keratitis
MONDO:0015291Mondo
Findings
No curated finding names stromal keratitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Herpes simplex (HSV) stromal keratitis is an infectious ocular disease of either necrotizing or non-necrotizing form, due to an HSV infection, and characterized by corneal stromal necrosis, inflammation, ulceration and infiltration by leukocytes. Corneal perforation and blindness can also occur in severe cases.
Definition from the Mondo Disease Ontology (MONDO:0015291), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Corneal stromal edemaHPOHP:0012040
- Very frequent (80% to 99% of cases)
- Deep anterior chamberHPOHP:0007765
- Very frequent (80% to 99% of cases)
- Open angle glaucomaHPOHP:0012108
- Very frequent (80% to 99% of cases)
- Reduced visual acuityHPOHP:0007663
- Very frequent (80% to 99% of cases)
- Blurred visionHPOHP:0000622
- Frequent (30% to 79% of cases)
- Conjunctival hyperemiaHPOHP:0030953
- Frequent (30% to 79% of cases)
- Corneal perforationHPOHP:0100583
- Frequent (30% to 79% of cases)
- Decreased corneal sensationHPOHP:0012155
- Frequent (30% to 79% of cases)
- Descemet Membrane FoldsHPOHP:0012039
- Frequent (30% to 79% of cases)
- EpiphoraHPOHP:0009926
- Frequent (30% to 79% of cases)
- Herpetiform corneal ulcerationHPOHP:0007812
- Frequent (30% to 79% of cases)
- Herpetiform vesiclesHPOHP:0031448
- Frequent (30% to 79% of cases)
Show the remaining 5
- Ocular hypertensionHPOHP:0007906
- Frequent (30% to 79% of cases)
- BlindnessHPOHP:0000618
- Occasional (5% to 29% of cases)
- KeratitisHPOHP:0000491
- Occasional (5% to 29% of cases)
- Low-grade feverHPOHP:0011134
- Occasional (5% to 29% of cases)
- MalaiseHPOHP:0033834
- Occasional (5% to 29% of cases)
Where it sits
- A kind of