steroid-responsive encephalopathy associated with autoimmune thyroiditis
Findings
No curated finding names steroid-responsive encephalopathy associated with autoimmune thyroiditis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare, acquired, neurological disease characterized by encephalopathy associated with elevated antithyroid antibodies, in the absence of other causes. Clinical presentation varies from minor cognitive impairment to status epilepticus and coma, and frequently includes seizures, confusion, speech disorder, memory impairment, ataxia and psychiatric manifestations.
Definition from the Mondo Disease Ontology (MONDO:0019385), read 2026-09-29. CC BY 4.0.
Features
24 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Acute encephalopathyHPOHP:0006846
- Obligate (100% of cases)
- Cerebral vasculitisHPOHP:0005318
- Very frequent (80% to 99% of cases)
- Hashimoto thyroiditisHPOHP:0000872
- Very frequent (80% to 99% of cases)
- Abnormal cerebral white matter morphologyHPOHP:0002500
- Frequent (30% to 79% of cases)
- ConfusionHPOHP:0001289
- Frequent (30% to 79% of cases)
- GoiterHPOHP:0000853
- Frequent (30% to 79% of cases)
- Hyponatremia
Show the remaining 12
- DepressionHPOHP:0000716
- Occasional (5% to 29% of cases)
- FeverHPOHP:0001945
- Occasional (5% to 29% of cases)
- Focal-onset seizureHPOHP:0007359
- Occasional (5% to 29% of cases)
- Generalized-onset seizureHPOHP:0002197
- Occasional (5% to 29% of cases)
- HeadacheHPOHP:0002315
- Occasional (5% to 29% of cases)
- ImmunodeficiencyHPOHP:0002721
- Occasional (5% to 29% of cases)
Where it sits
Other names
1 name
Resolves to: steroid-responsive encephalopathy associated with autoimmune thyroiditis
- Also called
- SREAT