staphylococcal necrotizing pneumonia
Findings
No curated finding names staphylococcal necrotizing pneumonia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Staphylococcal necrotizing pneumonia is a rare, bacterial, pulmonary infectious disease, caused by a Panton-Valentine leukocidin-producing Staphylococcus aureus strain, characterized by severe respiratory failure, extensive, rapidly progressing pneumonia and hemorrhagic lung necrosis. Patients typically present with influenza-like symptoms, such as fever, cough, and chest pain, as well as hemoptysis, hypotension, leukopenia, and severe respiratory symptoms that rapidly evolve to acute respiratory distress syndrome and septic shock. High mortality is associated.
Definition from the Mondo Disease Ontology (MONDO:0018183), read 2026-09-29. CC BY 4.0.
Features
38 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- CoughHPOHP:0012735
- Very frequent (80% to 99% of cases)
- DyspneaHPOHP:0002094
- Very frequent (80% to 99% of cases)
- Elevated erythrocyte sedimentation rateHPOHP:0003565
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- Increased total leukocyte countHPOHP:0001974
- Very frequent (80% to 99% of cases)
- PneumoniaHPOHP:0002090
- Very frequent (80% to 99% of cases)
- Respiratory distress
Show the remaining 26
- Elevated circulating C-reactive protein concentrationHPOHP:0011227
- Frequent (30% to 79% of cases)
- HypotensionHPOHP:0002615
- Frequent (30% to 79% of cases)
- HypoxemiaHPOHP:0012418
- Frequent (30% to 79% of cases)
- Increased circulating procalcitonin concentrationHPOHP:0032308
- Frequent (30% to 79% of cases)
- Increased total neutrophil countHPOHP:0011897
- Frequent (30% to 79% of cases)
- Nonproductive coughHPOHP:0031246
- Frequent (30% to 79% of cases)