ST2 diffuse large B-cell lymphoma
MONDO:0850472Mondo
Findings
No curated finding names ST2 diffuse large B-cell lymphoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A diffuse large B-cell lymphoma that is categorized as ST2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and ST2 DLBCLs often, but do not always, have missense or nonsense mutations affecting TET2 and NFKBIA. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting some combination of SGK1, ZFP36L1, SOCS1, HIST1H1E and CD83, which can be coding or non-coding.
Definition from the Mondo Disease Ontology (MONDO:0850472), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of