somatostatinoma
Findings
No curated finding names somatostatinoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare, usually malignant neuroendocrine tumor arizing from delta cells. This neoplasm produces large amounts of somatostatin, which may result in a syndrome characterized by diarrhea, steatorrhea, weight loss, and gastric hyposecretion. Sixty percent are found in the pancreas and 40% in the duodenum or jejunum. The peak incidence occurs between 40 and 60 years of age; women are affected more than men by 2:1.
Definition from the Mondo Disease Ontology (MONDO:0006976), read 2026-09-29. CC BY 4.0.
Features
35 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- Chronic fatigueHPOHP:0012432
- Frequent (30% to 79% of cases)
- ConstipationHPOHP:0002019
- Frequent (30% to 79% of cases)
- Diabetes mellitusHPOHP:0000819
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- Episodic abdominal painHPOHP:0002574
- Frequent (30% to 79% of cases)
- Gallbladder dysfunctionHPO
Show the remaining 23
- Poor appetiteHPOHP:0004396
- Frequent (30% to 79% of cases)
- SteatorrheaHPOHP:0002570
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- Abnormal abdomen morphologyHPOHP:0001438
- Occasional (5% to 29% of cases)
- AscitesHPOHP:0001541
- Occasional (5% to 29% of cases)
- Extrahepatic cholestasisHPOHP:0012334
- Occasional (5% to 29% of cases)
Where it sits
Other names
14 names
Resolves to: somatostatinoma
- Also called
- Delta cell tumorDelta cell tumoursomatostatin cell tumorsomatostatin producing tumorsomatostatin producing tumoursomatostatin-producing NETsomatostatin-producing neuroendocrine tumorsomatostatin-producing neuroendocrine tumoursomatostatin-producing tumorsomatostatin-producing tumourtumor of Delta cellstumor of the Delta cellstumour of Delta cellstumour of the Delta cells