serotonin syndrome
MONDO:0018546Mondo
Findings
No curated finding names serotonin syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Serotoninergic syndrome is characterized by an excess of serotonin in the central nervous system, associated with the use of various agents, including selective serotonin reuptake inhibitors (SSRIs).
Definition from the Mondo Disease Ontology (MONDO:0018546), read 2026-09-29. CC BY 4.0.
Features
34 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormality of the autonomic nervous systemHPOHP:0002270
- Very frequent (80% to 99% of cases)
- AnxietyHPOHP:0000739
- Frequent (30% to 79% of cases)
- ConfusionHPOHP:0001289
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- InsomniaHPOHP:0100785
- Frequent (30% to 79% of cases)
- IrritabilityHPOHP:0000737
- Frequent (30% to 79% of cases)
- Mental deteriorationHPOHP:0001268
- Frequent (30% to 79% of cases)
- MyoclonusHPOHP:0001336
- Frequent (30% to 79% of cases)
- NauseaHPOHP:0002018
- Frequent (30% to 79% of cases)
- RestlessnessHPOHP:0000711
- Frequent (30% to 79% of cases)
- TachycardiaHPOHP:0001649
- Frequent (30% to 79% of cases)
- TremorHPOHP:0001337
- Frequent (30% to 79% of cases)
Show the remaining 22
- Abnormal saccadic eye movementsHPOHP:0000570
- Occasional (5% to 29% of cases)
- AgitationHPOHP:0000713
- Occasional (5% to 29% of cases)
- ClonusHPOHP:0002169
- Occasional (5% to 29% of cases)
- Decreased vigilanceHPOHP:0032044
- Occasional (5% to 29% of cases)
- HyperhidrosisHPOHP:0000975
- Occasional (5% to 29% of cases)
- HyperreflexiaHPOHP:0001347
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: serotonin syndrome
- Also called
- serotonergic syndromeserotonin stormserotonin toxicityserotonin toxidrome