selective pituitary resistance to thyroid hormone
Findings
No curated finding names selective pituitary resistance to thyroid hormone yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Pituitary resistance to thyroid hormone is a rare, genetic thyroid disease, due to reduced pituitary gland responsiveness to thyroid hormone, characterized by mild to moderate hyperthyroidism in association with elevated circulating thyroid hormone levels, normal or elevated thyroid stimulating hormone, and no abnormalities of the pituitary gland on MRI. Patients present with diffuse large goiter, tachycardia, atrial fibrillation, weight loss and/or heat intolerance/perspiration, but no exophthalmos or anterior tibial mixedema.
Definition from the Mondo Disease Ontology (MONDO:0007784), read 2026-09-29. CC BY 4.0.
Where it sits
Other names
1 name
Resolves to: selective pituitary resistance to thyroid hormone
- Also called
- PRTH