schwannoma
Findings
No curated finding names schwannoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A benign, usually encapsulated slow growing tumor composed of Schwann cells. It affects peripheral and cranial nerves. It recurs infrequently and only rare cases associated with malignant transformation have been reported.
Definition from the Mondo Disease Ontology (MONDO:0002546), read 2026-09-29. CC BY 4.0.
Features
24 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal cranial nerve morphologyHPOHP:0001291
- Very frequent (80% to 99% of cases)
- Abnormal temporal bone morphologyHPOHP:0009911
- Very frequent (80% to 99% of cases)
- Abnormality of peripheral nervous system electrophysiologyHPOHP:0030177
- Very frequent (80% to 99% of cases)
- Peripheral schwannomaHPOHP:0009593
- Very frequent (80% to 99% of cases)
- SchwannomaHPOHP:0100008
- Very frequent (80% to 99% of cases)
- Scleral schwannomaHPOHP:0100011
- Very frequent (80% to 99% of cases)
- Vestibular schwannomaHPOHP:0009588
- Very frequent (80% to 99% of cases)
- AllodyniaHPOHP:0012533
- Frequent (30% to 79% of cases)
- Facial palsyHPOHP:0010628
- Frequent (30% to 79% of cases)
- Hearing abnormalityHPOHP:0000364
- Frequent (30% to 79% of cases)
- VertigoHPOHP:0002321
- Frequent (30% to 79% of cases)
- Abnormal esophagus morphologyHPOHP:0002031
- Occasional (5% to 29% of cases)
Reported absent (1)
- Malignant peripheral nerve sheath tumorHPOHP:0100697
Show the remaining 12
- Abnormal fibula morphologyHPOHP:0002991
- Occasional (5% to 29% of cases)
- Abnormal parotid gland morphologyHPOHP:0000197
- Occasional (5% to 29% of cases)
- Abnormality of the adrenal glandsHPOHP:0000834
- Occasional (5% to 29% of cases)
- Abnormality of the breastHPOHP:0000769
- Occasional (5% to 29% of cases)
- Abnormality of the larynxHPOHP:0001600
- Occasional (5% to 29% of cases)
- Abnormality of the liverHPOHP:0001392
- Occasional (5% to 29% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- DGCR8HGNC:2847
- Limited · PanelApp Australia · Autosomal dominant · 2025
Where it sits
Other names
7 names
Resolves to: schwannoma
- Also called
- benign neurilemmomabenign schwannomaneurilemmomaneurinomaperipheral fibroblastomaschwannoma (WHO grade I)schwannoma, benign