schizophrenia 15
MONDO:0013498Mondo
Findings
No curated finding names schizophrenia 15 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A schizophrenia that has material basis in a mutation of SHANK3 on chromosome 22q13.33.
Definition from the Mondo Disease Ontology (MONDO:0013498), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Juvenile onset · Young adult onset
HPO, annotations 2026-09-02
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- SchizophreniaHPOHP:0100753
- 4 of 4 reported patients
- Intellectual disabilityHPOHP:0001249
- 2 of 4 reported patients
- HyperactivityHPOHP:0000752
- 1 of 4 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SHANK3HGNC:14294
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
Where it sits
Other names
2 names
Resolves to: schizophrenia 15
- Also called
- schizophrenia type 15SCZD15