rhabdoid tumor
Findings
No curated finding names rhabdoid tumor yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An aggressive malignant embryonal neoplasm usually occurring during childhood. It is characterized by the presence of large cells with abundant cytoplasm, large eccentric nucleus, and a prominent nucleolus and it is associated with abnormalities of chromosome 22. It can arise from the central nervous system, kidney, and the soft tissues. The prognosis is poor.
Definition from the Mondo Disease Ontology (MONDO:0002728), read 2026-09-29. CC BY 4.0.
Features
24 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Cerebral palsyHPOHP:0100021
- Frequent (30% to 79% of cases)
- Cranial nerve paralysisHPOHP:0006824
- Frequent (30% to 79% of cases)
- FeverHPOHP:0001945
- Frequent (30% to 79% of cases)
- HeadacheHPOHP:0002315
- Frequent (30% to 79% of cases)
- HematuriaHPOHP:0000790
- Frequent (30% to 79% of cases)
- HypertensionHPOHP:0000822
- Frequent (30% to 79% of cases)
- Internal hemorrhageHPOHP:0011029
- Frequent (30% to 79% of cases)
- IrritabilityHPOHP:0000737
- Frequent (30% to 79% of cases)
- LymphadenopathyHPOHP:0002716
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
- Neoplasm of the central nervous systemHPOHP:0100006
- Frequent (30% to 79% of cases)
Show the remaining 12
- Neoplasm of the liverHPOHP:0002896
- Frequent (30% to 79% of cases)
- Oculomotor nerve palsyHPOHP:0012246
- Frequent (30% to 79% of cases)
- Poor appetiteHPOHP:0004396
- Frequent (30% to 79% of cases)
- Renal neoplasmHPOHP:0009726
- Frequent (30% to 79% of cases)
- Respiratory insufficiencyHPOHP:0002093
- Frequent (30% to 79% of cases)
- SarcomaHPOHP:0100242
- Frequent (30% to 79% of cases)
Where it sits
Other names
2 names
Resolves to: rhabdoid tumor
- Also called
- malignant rhabdoid tumorrhabdoid sarcoma