renal nutcracker syndrome
Findings
No curated finding names renal nutcracker syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare, syndromic renal disease characterized by the entrapment of left renal vein (LRV) between the superior mesenteric artery (SMA) and the abdominal aorta, resulting in increased luminal pressure, renal hilar varices, hematuria and, at the microscopic level, rupture of thin-walled veins into the collecting system in renal fornices.
Definition from the Mondo Disease Ontology (MONDO:0019105), read 2026-09-29. CC BY 4.0.
Features
25 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- DepressionHPOHP:0000716
- Frequent (30% to 79% of cases)
- Dilatation of mesenteric arteryHPOHP:0011934
- Frequent (30% to 79% of cases)
- Flank painHPOHP:0030157
- Frequent (30% to 79% of cases)
- HematuriaHPOHP:0000790
- Frequent (30% to 79% of cases)
- Low back painHPOHP:0003419
- Frequent (30% to 79% of cases)
- ProteinuriaHPOHP:0000093
- Frequent (30% to 79% of cases)
- Renal artery stenosisHPOHP:0001920
- Frequent (30% to 79% of cases)
- VaricoceleHPOHP:0012871
- Frequent (30% to 79% of cases)
- Varicose veinsHPOHP:0002619
- Frequent (30% to 79% of cases)
- AnemiaHPOHP:0001903
- Occasional (5% to 29% of cases)
- DysuriaHPOHP:0100518
- Occasional (5% to 29% of cases)
- FatigueHPOHP:0012378
- Occasional (5% to 29% of cases)
Show the remaining 13
- Microscopic hematuriaHPOHP:0002907
- Occasional (5% to 29% of cases)
- Pelvic painHPOHP:0034267
- Occasional (5% to 29% of cases)
- Vulval varicose veinHPOHP:0100677
- Occasional (5% to 29% of cases)
- Abdominal painHPOHP:0002027
- Very rare (1% to 4% of cases)
- Abnormal autonomic nervous system physiologyHPOHP:0012332
- Very rare (1% to 4% of cases)
- DysmenorrheaHPOHP:0100607
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
2 names
Resolves to: renal nutcracker syndrome
- Also called
- left renal vein entrapment syndromeRNS