renal hypoplasia
Findings
No curated finding names renal hypoplasia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Renal hypoplasia is a developmental anomaly in which one or both kidneys (unilateral or bilateral renal hypoplasia, respectively) have a deficit in the number of nephrons and may be small. Oligomeganephronia represents a severe variant of hypoplasia in which nephron number is reduced by 80% and nephrons are markedly hypertrophied.
Definition from the Mondo Disease Ontology (MONDO:0019637), read 2026-09-29. CC BY 4.0.
Features
20 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal renal cortex morphologyHPOHP:0011035
- Frequent (30% to 79% of cases)
- Abnormal renal morphologyHPOHP:0012210
- Frequent (30% to 79% of cases)
- Abnormal renal tubule morphologyHPOHP:0000091
- Frequent (30% to 79% of cases)
- Chronic kidney diseaseHPOHP:0012622
- Frequent (30% to 79% of cases)
- Decreased numbers of nephronsHPOHP:0005563
- Frequent (30% to 79% of cases)
- GlomerulomegalyHPOHP:0030162
- Frequent (30% to 79% of cases)
- Renal insufficiencyHPOHP:0000083
- Frequent (30% to 79% of cases)
- Abnormality of the ureterHPOHP:0000069
- Occasional (5% to 29% of cases)
- DehydrationHPOHP:0001944
- Occasional (5% to 29% of cases)
- HydronephrosisHPOHP:0000126
- Occasional (5% to 29% of cases)
- HypertensionHPOHP:0000822
- Occasional (5% to 29% of cases)
- Pelvic kidneyHPOHP:0000125
- Occasional (5% to 29% of cases)
Show the remaining 8
- PolydipsiaHPOHP:0001959
- Occasional (5% to 29% of cases)
- Premature birthHPOHP:0001622
- Occasional (5% to 29% of cases)
- ProteinuriaHPOHP:0000093
- Occasional (5% to 29% of cases)
- Recurrent urinary tract infectionsHPOHP:0000010
- Occasional (5% to 29% of cases)
- Small for gestational ageHPOHP:0001518
- Occasional (5% to 29% of cases)
- Unilateral renal agenesisHPOHP:0000122
- Occasional (5% to 29% of cases)
Where it sits
- Narrower terms (2)
Other names
1 name
Resolves to: renal hypoplasia
- Also called
- renal hypoplasia (disease)