punctate palmoplantar keratoderma type 2
Findings
No curated finding names punctate palmoplantar keratoderma type 2 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Punctate palmoplantar keratoderma type 2 is a type of isolated, punctate, hereditary palmoplantar keratoderma characterized by multiple, asymptomatic, 1 to 2 mm-long, firm, hyperkeratotic projections ("spiny keratosis") on the palms, soles and digits (typically confined to their volar and/or lateral aspects). Histopathologically, compact columnar parakeratosis over hypo- or agranular epidermis is observed.
Definition from the Mondo Disease Ontology (MONDO:0008292), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- PorokeratosisHPOHP:0200044
- Spinous keratoses of palms and solesHPOHP:0007613
Where it sits
- A kind of
Other names
3 names
Resolves to: punctate palmoplantar keratoderma type 2
- Also called
- PPKP2PPPPpunctate palmoplantar hyperkeratosis type 2