prostate cancer, hereditary, 1
Findings
No curated finding names prostate cancer, hereditary, 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene.
Definition from the Mondo Disease Ontology (MONDO:0011098), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Adult onset
HPO, annotations 2026-09-02
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Prostate cancerHPOHP:0012125
- 11 of 11 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- RNASELHGNC:10050
- Limited · Ambry Genetics · Autosomal dominant · 2018
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2022
Where it sits
- A kind of
Other names
4 names
Resolves to: prostate cancer, hereditary, 1
- Also called
- familial prostate cancer caused by mutation in RNASELprostate cancer 1prostate cancer, hereditary, type 1RNASEL familial prostate cancer