primary ciliary dyskinesia 35
Findings
No curated finding names primary ciliary dyskinesia 35 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the TTC25 gene.
Definition from the Mondo Disease Ontology (MONDO:0014910), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Neonatal onset
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- BronchiectasisHPOHP:0002110
- 3 of 3 reported patients
- Chronic otitis mediaHPOHP:0000389
- 3 of 3 reported patients
- Chronic rhinitisHPOHP:0002257
- 3 of 3 reported patients
- Chronic sinusitisHPOHP:0011109
- 3 of 3 reported patients
- Decreased nasal nitric oxideHPOHP:0033036
- 3 of 3 reported patients
- Nasal polyposisHPOHP:0100582
- 3 of 3 reported patients
- Productive coughHPOHP:0031245
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ODAD4HGNC:25280
- Definitive · ClinGen · Autosomal recessive · 2022
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2021
- Strong · G2P · Autosomal recessive · 2025
- Strong · PanelApp Australia · Autosomal recessive · 2025
Where it sits
- A kind of
Other names
6 names
Resolves to: primary ciliary dyskinesia 35
- Also called
- CILD35ciliary dyskinesia, primary, 35ciliary dyskinesia, primary, type 35primary ciliary dyskinesia caused by mutation in TTC25primary ciliary dyskinesia type 35TTC25 primary ciliary dyskinesia