pressure-induced localized lipoatrophy
Findings
No curated finding names pressure-induced localized lipoatrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Pressure-induced localized lipoatrophy is a rare, acquired, localized lipodystrophy characterized by band-like, horizontal, asymptomatic, lipoatrophic depressions with clinically normal overlying skin usually involving the anterolateral aspect of the thighs. An identifiable history of the repeated mechanical microtrauma due to occupational or postural habits is present.
Definition from the Mondo Disease Ontology (MONDO:0019556), read 2026-09-29. CC BY 4.0.
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- LipoatrophyHPOHP:0100578
- Obligate (100% of cases)
- Reduced subcutaneous adipose tissueHPOHP:0003758
- Very frequent (80% to 99% of cases)
- Regional abnormality of skinHPOHP:0011356
- Very frequent (80% to 99% of cases)
- Absence of subcutaneous fatHPOHP:0007485
- Frequent (30% to 79% of cases)
- ErythemaHPOHP:0010783
- Frequent (30% to 79% of cases)
- Inflammatory abnormality of the skinHPOHP:0011123
- Frequent (30% to 79% of cases)
- Skin nodule
Where it sits
- A kind of
Other names
2 names
Resolves to: pressure-induced localized lipoatrophy
- Also called
- lipoatrophia semicircularissemicircular lipoatrophy