premature ovarian failure 20
MONDO:0030975Mondo
Findings
No curated finding names premature ovarian failure 20 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Young adult onset
HPO, annotations 2026-09-02
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Elevated circulating follicle stimulating hormone levelHPOHP:0008232
- 2 of 2 reported patients
- Elevated circulating luteinizing hormone levelHPOHP:0011969
- 2 of 2 reported patients
- Female infertilityHPOHP:0008222
- 2 of 2 reported patients
- Secondary amenorrheaHPOHP:0000869
- 2 of 2 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MSH4HGNC:7327
- Strong · Ambry Genetics · Autosomal recessive · 2023
- Strong · PanelApp Australia · Autosomal recessive · 2025
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2022
Where it sits
- A kind of
Other names
1 name
Resolves to: premature ovarian failure 20
- Also called
- POF20