posttransplant acute limbic encephalitis
Findings
No curated finding names posttransplant acute limbic encephalitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Posttransplant acute limbic encephalitis is a rare, acquired, non-paraneoplastic limbic encephalitis disorder, that develops in the setting of treatment-related immunosuppression, typically after allogeneic hemapoietic stem cell transplantation, characterized by onset of confusion, headache, anterograde amnesia, seizures and/or loss of consciousness 2-6 weeks following transplantation. Bilateral, non-enhancing T2 hyperintensities in limbic structures are observed on magnetic resonance imaging. Mild cerebrospinal fluid pleocytosis and syndrome of inappropriate antidiuretic hormone secretion may also be associated.
Definition from the Mondo Disease Ontology (MONDO:0015595), read 2026-09-29. CC BY 4.0.
Features
23 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- CSF lymphocytic pleiocytosisHPOHP:0200149
- Frequent (30% to 79% of cases)
- CSF polymorphonuclear pleocytosisHPOHP:0012756
- Frequent (30% to 79% of cases)
- EEG with focal epileptiform dischargesHPOHP:0011185
- Frequent (30% to 79% of cases)
- HyperglycorrhachiaHPOHP:0031885
- Frequent (30% to 79% of cases)
- HyponatremiaHPOHP:0002902
- Frequent (30% to 79% of cases)
- Increased CSF protein concentrationHPOHP:0002922
- Frequent (30% to 79% of cases)
- Memory impairment
Show the remaining 11
- Abnormality of movementHPOHP:0100022
- Occasional (5% to 29% of cases)
- AnxietyHPOHP:0000739
- Occasional (5% to 29% of cases)
- AtaxiaHPOHP:0001251
- Occasional (5% to 29% of cases)
- Atypical behaviorHPOHP:0000708
- Occasional (5% to 29% of cases)
- Cognitive impairmentHPOHP:0100543
- Occasional (5% to 29% of cases)
- ConfusionHPOHP:0001289
- Occasional (5% to 29% of cases)
Where it sits
Other names
1 name
Resolves to: posttransplant acute limbic encephalitis
- Also called
- PALE