postpoliomyelitis syndrome
Findings
No curated finding names postpoliomyelitis syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis, 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.
Definition from the Mondo Disease Ontology (MONDO:0017416), read 2026-09-29. CC BY 4.0.
Features
18 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Muscle weaknessHPO · MondoHP:0001324
- Very frequent (80% to 99% of cases)
- PainHPOHP:0012531
- Very frequent (80% to 99% of cases)
- Abnormality of mental functionHPOHP:0011446
- Frequent (30% to 79% of cases)
- ArthralgiaHPOHP:0002829
- Frequent (30% to 79% of cases)
- Difficulty climbing stairsHPOHP:0003551
- Frequent (30% to 79% of cases)
- Excessive daytime somnolenceHPOHP:0001262
- Frequent (30% to 79% of cases)
- Fatigue
Show the remaining 6
- Muscle spasmHPOHP:0003394
- Occasional (5% to 29% of cases)
- Respiratory insufficiencyHPOHP:0002093
- Occasional (5% to 29% of cases)
- Skeletal muscle atrophyHPOHP:0003202
- Occasional (5% to 29% of cases)
- Sleep disturbanceHPOHP:0002360
- Occasional (5% to 29% of cases)
- HypoventilationHPOHP:0002791
- Very rare (1% to 4% of cases)
- Sleep apneaMondoHP:0010535
Where it sits
- A kind of
Other names
5 names
Resolves to: postpoliomyelitis syndrome
- Also called
- Post Polio Syndromepostpolio sequelaepostpolio syndromepostpoliomyelitic syndromepostpoliomyelitis sequelae