posterior cortical atrophy
MONDO:0018899Mondo
Findings
No curated finding names posterior cortical atrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Posterior Cortical Atrophy (PCA) is a rare progressive neurodegenerative disorder with a typical onset between 50-65 years of age characterized by progressive impairment of higher visual processing skills and other posterior cortical functions without any evidence of ocular abnormalities.
Definition from the Mondo Disease Ontology (MONDO:0018899), read 2026-09-29. CC BY 4.0.
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AlexiaHPOHP:0010523
- Very frequent (80% to 99% of cases)
- AnxietyHPOHP:0000739
- Very frequent (80% to 99% of cases)
- AtaxiaHPOHP:0001251
- Very frequent (80% to 99% of cases)
- Cerebral visual impairmentHPOHP:0100704
- Very frequent (80% to 99% of cases)
- ConfusionHPOHP:0001289
- Very frequent (80% to 99% of cases)
- Disturbed sensory perceptionHPOHP:0010524
- Very frequent (80% to 99% of cases)
- DyscalculiaHPOHP:0002442
- Very frequent (80% to 99% of cases)
- DysgraphiaHPOHP:0010526
- Very frequent (80% to 99% of cases)
- Finger agnosiaHPOHP:0010525
- Very frequent (80% to 99% of cases)
- Oculomotor apraxiaHPOHP:0000657
- Very frequent (80% to 99% of cases)
- Abnormality of visionHPOHP:0000504
- Frequent (30% to 79% of cases)
- Color vision defectHPOHP:0000551
- Frequent (30% to 79% of cases)
Show the remaining 9
- DyslexiaHPOHP:0010522
- Frequent (30% to 79% of cases)
- Limb apraxiaHPOHP:0030217
- Frequent (30% to 79% of cases)
- PhotophobiaHPOHP:0000613
- Frequent (30% to 79% of cases)
- Abnormal rapid eye movement sleepHPOHP:0002494
- Occasional (5% to 29% of cases)
- InertiaHPOHP:0030216
- Occasional (5% to 29% of cases)
- Language impairmentHPOHP:0002463
- Occasional (5% to 29% of cases)
Where it sits
Other names
3 names
Resolves to: posterior cortical atrophy
- Also called
- Benson syndromebiparietal Alzheimer diseasePCA