polymyositis
MONDO:0019127Mondo
Findings
No curated finding names polymyositis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare idiopathic inflammatory myopathy characterized by symmetric proximal muscle weakness and elevated muscle enzymes.
Definition from the Mondo Disease Ontology (MONDO:0019127), read 2026-09-29. CC BY 4.0.
Features
60 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal muscle fiber morphologyHPOHP:0004303
- Very frequent (80% to 99% of cases)
- ArthralgiaHPOHP:0002829
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- CoughHPOHP:0012735
- Very frequent (80% to 99% of cases)
- Elevated circulating aldolase concentrationHPOHP:0012544
- Very frequent (80% to 99% of cases)
- Elevated circulating creatine kinase activityHPOHP:0003236
- Very frequent (80% to 99% of cases)
- EMG abnormalityHPOHP:0003457
- Very frequent (80% to 99% of cases)
- HypotoniaHPOHP:0001252
- Very frequent (80% to 99% of cases)
- Proximal muscle weaknessHPOHP:0003701
- Very frequent (80% to 99% of cases)
- Abnormal pulmonary interstitial morphologyHPOHP:0006530
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- Anti-alanyl-tRNA synthetase antibody positivityHPOHP:0034145
- Frequent (30% to 79% of cases)
Show the remaining 48
- Anti-aminoacyl-tRNA synthetase antibody positivityHPOHP:0034147
- Frequent (30% to 79% of cases)
- Anti-asparaginyl-tRNA synthetase antibody positivityHPOHP:0034151
- Frequent (30% to 79% of cases)
- Anti-glycyl tRNA-synthetase antibody positivityHPOHP:0034146
- Frequent (30% to 79% of cases)
- Anti-histidyl tRNA synthetase antibody positivityHPOHP:0034152
- Frequent (30% to 79% of cases)
- Anti-isoleucyl tRNA-synthetase antibody positivityHPOHP:0034148
- Frequent (30% to 79% of cases)
- Anti-phenylalanyl tRNA synthetase antibody positivityHPOHP:0034149
Where it sits
- Narrower terms (2)
Other names
1 name
Resolves to: polymyositis
- Also called
- PM