polyembryoma
Findings
No curated finding names polyembryoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Polyembryoma is a type oftumor that develops from the cells of the gonads (testes in men or ovaries in women). Such tumors are called germ cell tumors. Polyembryomas have a distinctivelook because they are composed of many parts that are shaped like embryos, one of the earliest stages of a developing human during pregnancy. Symptoms of a polyembryoma may include an unusual bump or mass in the abdomen which can cause pain in some individuals; puberty at an unusually young age (known as precocious puberty); or irregularities in a female's menstruation. Treatment begins with surgery and may be followed by chemotherapy and/or radiation therapy. The cause of polyembryoma is not yet known.
Definition from the Mondo Disease Ontology (MONDO:0015863), read 2026-09-29. CC BY 4.0.
Features
19 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal circulating gonadotropin concentrationHPOHP:0030338
- Frequent (30% to 79% of cases)
- Gonadal neoplasmHPOHP:0010785
- Frequent (30% to 79% of cases)
- Neuroectodermal neoplasmHPOHP:0030061
- Frequent (30% to 79% of cases)
- Abdominal massHPOHP:0031500
- Occasional (5% to 29% of cases)
- Abdominal painHPOHP:0002027
- Occasional (5% to 29% of cases)
- Abnormal mediastinum morphologyHPOHP:0045026
- Occasional (5% to 29% of cases)
- Abnormal onset of bleeding
Show the remaining 7
- Abnormality of the endocrine systemHPOHP:0000818
- Very rare (1% to 4% of cases)
- FeverHPOHP:0001945
- Very rare (1% to 4% of cases)
- Increased serum serotoninHPOHP:0003144
- Very rare (1% to 4% of cases)
- Increased serum testosterone levelHPOHP:0030088
- Very rare (1% to 4% of cases)
- Irregular menstruationHPOHP:0000858
- Very rare (1% to 4% of cases)
- Isosexual precocious pubertyHPOHP:0008236
- Very rare (1% to 4% of cases)
Where it sits
- Narrower terms (2)