pituitary adenocarcinoma
Findings
No curated finding names pituitary adenocarcinoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare adenocarcinoma with poor prognosis, arising from the adenohypophysial cells of the anterior lobe of the pituitary gland or pre-existing adenomas. The majority are hormonally functioning neoplasms, usually producing prolactin or ACTH. The diagnosis is based on the presence of metastases. Syndromes associated with pituitary gland carcinomas include hyperprolactinemia, Cushing disease, and acromegaly.
Definition from the Mondo Disease Ontology (MONDO:0017582), read 2026-09-29. CC BY 4.0.
Features
22 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Pituitary carcinomaHPOHP:0011763
- Obligate (100% of cases)
- HeadacheHPOHP:0002315
- Very frequent (80% to 99% of cases)
- Increased circulating ACTH levelHPOHP:0003154
- Very frequent (80% to 99% of cases)
- Increased circulating prolactin concentrationHPOHP:0000870
- Very frequent (80% to 99% of cases)
- Malignant neoplasm of the central nervous systemHPOHP:0100836
- Very frequent (80% to 99% of cases)
- Pituitary corticotropic cell adenomaHPOHP:0008291
- Very frequent (80% to 99% of cases)
Show the remaining 10
- Abnormal central motor functionHPOHP:0011442
- Occasional (5% to 29% of cases)
- AtaxiaHPOHP:0001251
- Occasional (5% to 29% of cases)
- Elevated circulating growth hormone concentrationHPOHP:0000845
- Occasional (5% to 29% of cases)
- Hearing impairmentHPOHP:0000365
- Occasional (5% to 29% of cases)
- HyperpituitarismHPOHP:0010514
- Occasional (5% to 29% of cases)
- Pituitary growth hormone cell adenomaHPOHP:0011760
- Occasional (5% to 29% of cases)
Where it sits
Other names
8 names
Resolves to: pituitary adenocarcinoma
- Also called
- carcinoma of pituitarycarcinoma of pituitary glandcarcinoma of the pituitarycarcinoma of the pituitary glandpituitary adenocarcinoma (disease)pituitary carcinomapituitary gland adenocarcinomapituitary gland carcinoma