pineoblastoma
Findings
No curated finding names pineoblastoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Pineoblastoma is a rare, malignant type of supratentorial primitive neuroectodermal tumor (sPNET), found mainly in children (less than 10% of cases are reported in adults), and located in the pineal region of the brain but that can metastasize along the neuroaxis. As it is the most aggressive of the pineal parenchymal tumors, it is usually associated with a poor prognosis.
Definition from the Mondo Disease Ontology (MONDO:0016722), read 2026-09-29. CC BY 4.0.
Features
19 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- PinealomaHPOHP:0010799
- Obligate (100% of cases)
- HeadacheHPOHP:0002315
- Very frequent (80% to 99% of cases)
- Atypical behaviorHPOHP:0000708
- Frequent (30% to 79% of cases)
- Cognitive impairmentHPOHP:0100543
- Frequent (30% to 79% of cases)
- Increased intracranial pressureHPOHP:0002516
- Frequent (30% to 79% of cases)
- Memory impairmentHPOHP:0002354
- Frequent (30% to 79% of cases)
- Progressive neurologic deteriorationHPOHP:0002344
- Frequent (30% to 79% of cases)
- Amaurosis fugaxHPOHP:0100576
- Occasional (5% to 29% of cases)
- Impaired convergenceHPOHP:0000619
- Occasional (5% to 29% of cases)
- Midline brain calcificationsHPOHP:0007045
- Occasional (5% to 29% of cases)
- PapilledemaHPOHP:0001085
- Occasional (5% to 29% of cases)
- ParalysisHPOHP:0003470
- Occasional (5% to 29% of cases)
Show the remaining 7
- Progressive visual field defectsHPOHP:0007987
- Occasional (5% to 29% of cases)
- Reduced visual acuityHPOHP:0007663
- Occasional (5% to 29% of cases)
- RetinoblastomaHPOHP:0009919
- Occasional (5% to 29% of cases)
- SeizureHPOHP:0001250
- Occasional (5% to 29% of cases)
- Sensory neuropathyHPOHP:0000763
- Occasional (5% to 29% of cases)
- LethargyHPOHP:0001254
- Very rare (1% to 4% of cases)
Where it sits
- Narrower terms (1)
Other names
18 names
Resolves to: pineoblastoma
- Also called
- pineal gland PNETpineal gland primitive neuroectodermal neoplasmpineal gland primitive neuroectodermal tumorpineal gland primitive neuroectodermal tumourpineal PNETpineal primitive neuroectodermal neoplasmpineal primitive neuroectodermal tumorpineal primitive neuroectodermal tumourpineoblastoma (WHO grade IV)pineoblastoma, malignantPNET of pineal glandPNET of the pineal glandprimitive neuroectodermal neoplasm of pineal glandprimitive neuroectodermal neoplasm of the pineal glandprimitive neuroectodermal tumor of pineal gland