persistent polyclonal B-cell lymphocytosis
MONDO:0011672Mondo
Findings
No curated finding names persistent polyclonal B-cell lymphocytosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare, generally benign, lymphoproliferative hematological disease characterized by: chronic, stable, persistent, polyclonal lymphocytosis of memory B-cell origin, the presence of binucleated lymphocytes in the peripheral blood, and a polyclonal increase in serum immunoglobulin M (IgM). Patients are most frequently asymptomatic or may present with mild splenomegaly.
Definition from the Mondo Disease Ontology (MONDO:0011672), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
2 names
Resolves to: persistent polyclonal B-cell lymphocytosis
- Also called
- persistent polyclonal B-cell lymphocytosis with binucleated lymphocytesPPBL