pemphigus vulgaris
MONDO:0008219Mondo
Findings
No curated finding names pemphigus vulgaris yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Pemphigus is a group of chronic autoimmune skin diseases characterized by blister formations on the outer layer of the skin and the mucous membranes. Three clinical forms have been characterized, of which pemphigus vulgaris is the most frequent (75%).
Definition from the Mondo Disease Ontology (MONDO:0008219), read 2026-09-29. CC BY 4.0.
Features
20 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AcantholysisHPOHP:0100792
- Very frequent (80% to 99% of cases)
- Atypical scarring of skinHPOHP:0000987
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- Erosion of oral mucosaHPOHP:0031446
- Very frequent (80% to 99% of cases)
- Feeding difficulties in infancyHPOHP:0008872
- Very frequent (80% to 99% of cases)
- Oral mucosal blistersHPOHP:0200097
- Very frequent (80% to 99% of cases)
- Recurrent cutaneous abscess formationHPOHP:0100838
- Very frequent (80% to 99% of cases)
- Recurrent infectionsHPOHP:0002719
- Very frequent (80% to 99% of cases)
- UrticariaHPOHP:0001025
- Very frequent (80% to 99% of cases)
- Weight lossHPOHP:0001824
- Very frequent (80% to 99% of cases)
- Abnormal blistering of the skinHPOHP:0008066
- Frequent (30% to 79% of cases)
- Anti-desmoglein-1 antibody positivityHPOHP:4000013
- Frequent (30% to 79% of cases)
Show the remaining 8
- Anti-desmoglein-3 antibody positivityHPOHP:4000014
- Frequent (30% to 79% of cases)
- AnxietyHPOHP:0000739
- Frequent (30% to 79% of cases)
- DepressionHPOHP:0000716
- Frequent (30% to 79% of cases)
- Feeding difficultiesHPOHP:0011968
- Frequent (30% to 79% of cases)
- Suprabasal cleavageHPOHP:0034194
- Frequent (30% to 79% of cases)
- Alopecia of scalpHPOHP:0002293
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
- Narrower terms (1)