pediatric-onset Graves disease
Findings
No curated finding names pediatric-onset Graves disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare endocrine disease characterized by the presence of serum autoantibodies against thyroid-stimulating hormone receptors, leading to excessive thyroid hormone production and a swollen thyroid gland. Children with this disease typically experience symptoms of an overactive thyroid, including rapid heartbeat, weight loss, tremors, and excessive sweating.
Definition from the Mondo Disease Ontology (MONDO:0033925), read 2026-09-29. CC BY 4.0.
Features
48 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- Graves diseaseHPOHP:0100647
- Very frequent (80% to 99% of cases)
- Increased circulating T4 concentrationHPOHP:0031506
- Very frequent (80% to 99% of cases)
- Sinus tachycardiaHPOHP:0011703
- Very frequent (80% to 99% of cases)
- Thyrotoxicosis with diffuse goiterHPOHP:0011784
- Very frequent (80% to 99% of cases)
- Abnormal eyelid morphologyHPOHP:0000492
- Frequent (30% to 79% of cases)
- Accelerated skeletal maturation
Show the remaining 36
- FlushingHPOHP:0031284
- Frequent (30% to 79% of cases)
- GoiterHPOHP:0000853
- Frequent (30% to 79% of cases)
- HepatomegalyHPOHP:0002240
- Frequent (30% to 79% of cases)
- HyperactivityHPOHP:0000752
- Frequent (30% to 79% of cases)
- HyperhidrosisHPOHP:0000975
- Frequent (30% to 79% of cases)
- Hyperkinetic movementsHPOHP:0002487
- Frequent (30% to 79% of cases)
Where it sits
- A kind of