parkinsonism with polyneuropathy
MONDO:0036193Mondo
Findings
No curated finding names parkinsonism with polyneuropathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AnxietyHPOHP:0000739
- 5 of 5 reported patients
- BradykinesiaHPOHP:0002067
- 8 of 8 reported patients
- Decreased amplitude of sensory action potentialsHPOHP:0007078
- 5 of 5 reported patients
- Decreased compound muscle action potential amplitudeHPOHP:0033383
- 5 of 5 reported patients
- Parkinsonism with favorable response to dopaminergic medicationHPOHP:0002548
- 8 of 8 reported patients
- RigidityHPOHP:0002063
- 8 of 8 reported patients
- Decreased motor nerve conduction velocityHPOHP:0003431
- 4 of 5 reported patients
- PolyneuropathyHPOHP:0001271
- 4 of 5 reported patients
- Resting tremorHPOHP:0002322
- 6 of 8 reported patients
- Diffuse cerebral atrophyHPOHP:0002506
- 3 of 5 reported patients
- DepressionHPOHP:0000716
- 2 of 5 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- UQCRC1HGNC:12585
- Limited · Ambry Genetics · Autosomal dominant · 2025
- Limited · Labcorp Genetics (formerly Invitae) · Unknown · 2021