parkinsonism with dementia of Guadeloupe
MONDO:0019977Mondo
Findings
No curated finding names parkinsonism with dementia of Guadeloupe yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Parkinsonism with dementia of Guadeloupe is characterized by symmetrical bradykinesia, predominantly axial rigidity, postural instability with early falls and cognitive decline with prominent features of frontal lobe dysfunction.
Definition from the Mondo Disease Ontology (MONDO:0019977), read 2026-09-29. CC BY 4.0.
Features
26 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- BradykinesiaHPOHP:0002067
- Very frequent (80% to 99% of cases)
- ParkinsonismHPOHP:0001300
- Very frequent (80% to 99% of cases)
- RigidityHPOHP:0002063
- Very frequent (80% to 99% of cases)
- Abnormal autonomic nervous system physiologyHPOHP:0012332
- Frequent (30% to 79% of cases)
- Action tremorHPOHP:0002345
- Frequent (30% to 79% of cases)
- ApraxiaHPOHP:0002186
- Frequent (30% to 79% of cases)
- Autonomic bladder dysfunctionHPOHP:0005341
- Frequent (30% to 79% of cases)
- Cerebral cortical atrophyHPOHP:0002120
- Frequent (30% to 79% of cases)
- DementiaHPOHP:0000726
- Frequent (30% to 79% of cases)
- DystoniaHPOHP:0001332
- Frequent (30% to 79% of cases)
- EMG: myopathic abnormalitiesHPOHP:0003458
- Frequent (30% to 79% of cases)
- Frontal lobe dementiaHPOHP:0000727
- Frequent (30% to 79% of cases)
Reported absent (1)
- Lewy bodiesHPOHP:0100315
Show the remaining 14
- HallucinationsHPOHP:0000738
- Frequent (30% to 79% of cases)
- Hypometric saccadesHPOHP:0000571
- Frequent (30% to 79% of cases)
- Midline brain calcificationsHPOHP:0007045
- Frequent (30% to 79% of cases)
- MyoclonusHPOHP:0001336
- Frequent (30% to 79% of cases)
- Orthostatic hypotensionHPOHP:0001278
- Frequent (30% to 79% of cases)
- Palmomental reflexHPOHP:0030902
- Frequent (30% to 79% of cases)
Where it sits
- A kind of